Cancer

Research Coordinator

Dr. Angel García Martín

Description

Any cell therapy effort based the use of stem cells needs to make sure that there is no risk of oncogenic transformation in the cells used as therapeutical agents therefore ensuring biosafety.

It has been recently suggested that the aberrant alteration of the mechanisms that control tissue homeostasis on stem cells may be the origin of tumors. Therefore investigating the role fo stem cells in cancer we will get insight into controlling the growth of stem cells being used in therapy.

The program on Cancer defines a transversal line through the other disease oriented programs towards understanding the mechanisms of stem cell transformation with an interest in biosaftey. As a starting point the program is focused on breast cancer and mammary stem cells as experimental model.

Research agreements and special collaborations

The Cancer program hold active collaboration with:

Biobide SL to develop functional model for drug screening specific for cancer stem cells.

Breast Cancer Stem Cells Network funded by obra social de kutxa, which integrates the research groups of:

Carmen Ramírez Castilljo, CRIB Universidad de Castilla La Mancha (Albacete)
Enrique Poblet, Universidad de Castilla La Mancha (Albacete)
Joaquín Dopazo, Centro de Investigación Príncipe Felipe (Valencia)
Isidro Sánchez García, Pedro Lazo and Jesus Pérez Losada, Centro de Investigación del Cáncer (Salamanca)